Molecular Physiology And Developmental Biology - 962 Words

Dr. Elizabeth Ables is an assistant professor at East Carolina University, in Greenville, North Carolina. She has worked there since 2013. Dr. Ables received her BS degree from St. Andrews University and her Ph.D. in Molecular Physiology and Developmental Biology from Vanderbilt University. She studied how the pancreas precursor cells are led by a cascade of transcription factors during development to become insulin-producing beta cells, while using transgenic mice and immunofluorescence microscopy to examine the topic. Her current studies resulted in the discovery that the steroid hormone ecdysone, which directly controls Drosophila germline stem cell activity. These studies expanded her ability to design experiments significant for†¦show more content†¦We learned tissue homeostasis is a balance between cell division, specialization, and turnover time. Normal cells have a plethora of specialized cells and with proliferation there tends to be a loss of specialized function. Her interest in stem cells came with some problems. First, all cells come from other cells. Secondly, specialized cells tend to divide very infrequently. Therefore, she began studying the germline cells of fruit flies because the cell cycle is very similar to humans. She wanted to study stem signals and their complex connections to determine the cell fate. Such as in the Drosophila uterine cells, there is a cluster of cells in which only one will become the final egg cell, the others are nurse cells that monitor the egg. The fate of these cells is predetermined by genes and were illustrated through immunofluorescence microscopy. During her presentation she held the attention of entire audience with the use of direct eye contact, and did not need to look at note cards or reference the slides unless directing the audience through a figure. She also spoke with respectable volume and articulation to keep the audience interested and emphasize key points. I like that she moved around a bi t while she spoke. She also made the class very informal, which helped to make it more comfortable to ask questions. She seemed very comfortable with her research and could answer all questions presented to her by the audience. She was very knowledgeable andShow MoreRelatedZoology Essay1264 Words   |  6 Pageszoology in his 37-volume treatise called Historia Naturalis. Although widely read during the Middle Ages, they are little more than a collection of folklore, myth, and superstition. One of the more influential figures in the history of physiology, the Greek physician Galen, dissected farm animals, monkeys, and other mammals and described many features accurately, although some were wrongly applied to the human body. His misconceptions, especially with regard to the movement ofRead MoreHealthcare Is Evolving And Applying New Innovations Into Its Field1417 Words   |  6 Pagesis a disciplinary field that involves both science/ health and technology (Hoyt, 2010). Bioinformatics is a field that combines, â€Å"computer science with biological and biomedical sciences such as chemistry, cell biology, developmental biology, genetics, genomics, and physiology† (Moore, 2007). It began with the development of DNA and protein sequencing, along with the increasing expansion of digital computers and biological databases (Hagen, 2000). One of the main goals of bioinformatics isRead MoreRole Of Homeobox Geness1022 Words   |  5 Pagesultimate regulators of development; however – mutations in the homeobox genes – specifically – HOXC10 are oncogenic (by gain-of-function mutations) and aid in the proliferation of certain cancer types and developmental disorders. 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Their experiments analyzed groups of children who were either in institutional or placed into foster care. They assessed many developmental indicators such as â€Å"cognitive function, social-emotional development, attachment, [and] problem behaviors† (p. 17), and often found a significantly higher risk of emotional malfunctioning from the care-as-usual, or institutionalized, group. SuchRead MoreHuman Aging And Cognition And Memory Storage869 Words   |  4 Pages(A) SIGNIFICANCE: Despite the advances in our understanding of aging [1,2,3,4], the physiological and molecular correlates of aging-depende nt alterations in specific neurons that underlie learning and memory storage are poorly understood. Such information is essential to delineate molecular underpinnings of aging-related changes to develop novel strategies for therapeutic intervention of the aging-associated specific deficits in learning and memory storage. 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